New Study Provides More Insight into Male Pattern Baldness

A new study shows links between a gene and a very rare condition which develops ‘peachy fuzzy’ hair, which could possibly provide a lot more information into baldness, especially in males.

The co-author of the study, Angela M. Christiano, Director, Center for Human Genetics, Columbia University says the new finding might not mean an immediate new cure or treatment for baldness, but it is just a tiny bit of information that might help solve the problem. She said that the new information gives researchers more insight into shrinkage, which is one part of male pattern baldness.

Baldness in most cases does not mean that hair stops growing altogether. Instead, hair growth is much lesser, and the hair that grows is very fine and short – which is almost like the fuzz on a peach. This means that the hair follicle is not dead, and functions to some extent – having the potential to grow some kind of hair.

This exact problem is also part of a rare disease – hereditary hypotrichosis, which begins right from birth.

The study conducted by Christiano and other researchers involved them scrutinizing the genetic makeup of three families who had inherited hereditary hypotrichosis. During the research carried out, the team of researchers found a gene which showed a mutation responsible for the rare condition.
Named APCDD1, the gene is situated close to chromosome 18 which in other studies shows a connection to hair loss. It also seems to block a pathway that has been proven to control the growth of hair in mice, but has not been linked too closely to humans.